Dr. Henry N Higgs' lab at Dartmouth College studies the dynamic interplay between the actin cytoskeleton and mitochondria in mammalian cells. The team focuses on understanding how transient actin structures influence mitochondrial function and energy metabolism, particularly in relation to diseases linked to dysfunctional mitochondria. Their research has significant implications for various cellular processes and could lead to insights in treating conditions such as Charcot-Marie-Tooth disease and focal segmental glomerulosclerosis.

Dr. James B Moseley's lab at Dartmouth College studies how cells control their size and shape, focusing on basic cellular mechanisms that can contribute to diseases like cancer. By using fission yeast as a model organism, the lab explores the processes involved in cell growth and division. Their interdisciplinary approach combines genetics and various microscopy techniques to uncover important signals that regulate these fundamental biological functions.

Dr. Surachai Supattapone's lab at Dartmouth College focuses on understanding prion diseases, which are caused by misfolded proteins that lead to neurodegenerative disorders such as Creutzfeldt-Jakob disease. The lab uses advanced genetic screening techniques to map the molecular pathways that control the metabolism of prion proteins, aiming to identify potential new targets for drug therapy. Their research not only enhances our knowledge of prion biology but also contributes to the development of therapeutic strategies for these fatal brain diseases.