Dr. Sebastian Klinge's lab at Rockefeller University studies how ribosomes, the molecular machines responsible for protein synthesis, are assembled in cells. The lab focuses on understanding the complex process of ribosome assembly, particularly the early stages that occur in the nucleolus. By integrating advanced techniques like cryo-electron microscopy and AI-based tools, the lab aims to uncover the mechanisms involved in this critical process and how errors in ribosome assembly can lead to blood disorders known as ribosomopathies.

Dr. Robert G. Roeder's lab at Rockefeller University focuses on understanding how specific proteins interact to control the formation and function of fat cells, which play a crucial role in metabolic health. The lab uses a combination of biochemical techniques and animal studies to explore how these interactions can impact conditions like obesity and diabetes. This research aims to uncover new potential treatments for metabolic disorders by examining the underlying mechanisms of fat cell behavior.