Dr. Sally Molloy's lab at the University of Maine focuses on understanding how certain viruses, known as prophages, help mycobacteria resist antibiotics. This research is important because infections caused by drug-resistant mycobacteria present a major public health challenge. By investigating the mechanisms that these prophages use to alter gene expression and enhance bacterial survival, the lab aims to provide insights that could improve treatment options for resistant infections.

Robert T. Wheeler's lab at the University of Maine Orono focuses on understanding how certain strains of Candida yeast cause vaginal infections (VVC) in some women while remaining harmless in others. The lab investigates the mechanisms by which these fungal strains can trigger inflammation and lead to painful symptoms, aiming to identify specific virulence factors that could improve diagnosis and treatment options. Their innovative approach combines genomic analyses and in vitro assays, which may ultimately transform the way we view and manage candidiasis.