Dr. Karsten R.O. Hazlett's lab focuses on developing effective vaccines against tularemia, a severe disease caused by the bacterium Francisella tularensis, which poses significant health risks to humans. The lab is currently advancing a promising vaccine candidate through testing in non-human primates to ensure its efficacy before potential human trials. Their work combines various disciplines, including bacteriology and biostatistics, to understand how vaccines function and identify correlates of protection that predict vaccine effectiveness.