Dr. Marc-Jan Gubbels' lab focuses on understanding how certain parasites, like those causing malaria and toxoplasmosis, divide and replicate within host cells. They explore the diverse mechanisms of cell division in these parasites using cutting-edge techniques, including single-cell sequencing. The goal is to not only uncover the complexities behind apicomplexan biology but also to aid in developing new treatments for these significant human health threats.

Kenneth C. Williams' lab at Boston College focuses on understanding how HIV and SIV can persist in the brain despite effective treatment. The research investigates specific immune cells in the brain called perivascular macrophages, which may serve as reservoirs for these viruses. By studying how these cells migrate out of the brain and contribute to viral rebound after treatment stops, the lab aims to develop new strategies for eradicating these persistent infections.

Dr. Welkin E Johnson's lab at Boston College studies how certain viruses, specifically lentiviruses like HIV-1 and HIV-2, interact with proteins in their host cells to invade them. They focus on a protein called Nup358, which plays a critical role in the virus's ability to enter the cell nucleus and replicate. By examining these interactions through various scientific techniques, the lab aims to uncover how these viruses have evolved to overcome host defenses and what this means for understanding and treating viral infections.