Clark A. Lindgren's research lab at Grinnell College focuses on understanding how signals from muscles regulate neurotransmitter release at the neuromuscular junction, particularly through a process called presynaptic homeostatic potentiation (PHP). The lab investigates the role of pH and other ionic factors in this communication, aiming to identify the mechanisms that allow muscles to adjust the strength of their signals to nerves. Undergraduate students play a crucial role in this research, gaining hands-on experience in the laboratory while contributing to important discoveries in neuroscience.