Dr. James P. Luyendyk's lab studies how the blood protein von Willebrand Factor (VWF) affects the repair of liver injuries caused by an overdose of acetaminophen, a common pain medication. They aim to discover ways to enhance liver recovery by targeting VWF and its interactions with platelets. The lab works closely with a network of physician-scientists and utilizes advanced genetic models and therapeutic strategies to address acute liver failure, which currently has limited treatment options.