Sujit Basu · Biology
Dr. Sujit Basu's research lab at Ohio State University focuses on advancing cancer treatment through immunotherapy. They specifically study the blockade of the CD200R pathway, which affects immune cell behaviors in the tumor environment. By understanding how to manipulate immune responses, Dr. Basu's team aims to improve the effectiveness of cancer therapies, potentially enhancing the way we treat various malignancies.
Aharon G Freud · Biology
Dr. Aharon G Freud's lab at Ohio State University studies natural killer (NK) cells, which are crucial for the immune system's ability to fight cancer. They focus on understanding how these cells develop in healthy situations and how their function is altered during endometrial carcinoma, a common type of cancer affecting women. By investigating the cellular and molecular mechanisms behind NK cell development, the lab aims to discover new ways to boost the immune response against cancer.
Yasuko Rikihisa · Biology
Dr. Yasuko Rikihisa's lab at Ohio State University focuses on understanding how the bacteria Anaplasma phagocytophilum, responsible for human granulocytic anaplasmosis, survive and replicate inside human cells. The lab studies how these bacteria hijack host cell machinery to acquire nutrients and evade the immune response. By investigating the molecular mechanisms involved, the research aims to uncover potential new treatments for this emerging tick-borne disease.
Sarah M Short · Biology
Dr. Sarah M Short's lab at Ohio State University studies how bacteria affect the life traits and mating success of male Aedes aegypti mosquitoes, which are important for controlling mosquito populations and preventing diseases. The lab investigates how different bacterial communities can influence mosquito characteristics like longevity and mating success, as well as the role of vitamins in these interactions. This research aims to improve methods for mass rearing sterile males used in population control strategies.