Dr. Jason W. Botten's lab at the University of Vermont focuses on understanding how certain viruses, specifically arenaviruses, produce defective particles that can influence both viral infection and host health. The lab investigates the cellular mechanisms that regulate these defective particles and their role in viral persistence within animal hosts, particularly rodents. By exploring these interactions, the research could provide insights into how zoonotic viruses impact public health.

Dr. Yvonne M. W. Janssen-Heininger's lab at the University of Vermont studies lung cancer, focusing on how a molecular process involving a protein called glutaredoxin affects cancer cell survival and resistance to treatment. The lab is investigating how changes in glutathione metabolism can influence lung tumor growth and how these insights can lead to potential new therapies for lung cancer patients. By understanding the cancer's metabolic adaptations, the lab aims to develop strategies to enhance the effectiveness of existing treatments like cisplatin.