Dr. Colleen K. Jackson-Cook's lab at Virginia Commonwealth University focuses on understanding how aging affects our cells at a genetic level. They conduct a long-term study on twins to explore how genetics and environment influence the presence of cytosolic DNA, which may play a role in age-related health issues. By analyzing how this DNA interacts with other biological markers of aging, the lab aims to uncover potential treatments for age-related diseases.

Dr. Senthil Kumar Radhakrishnan's lab focuses on enhancing the effectiveness of cancer therapies, particularly through the study of proteases. They are specifically investigating the DDI2 protease, which helps cancer cells survive during treatments with proteasome inhibitors used in multiple myeloma. By identifying small molecule inhibitors of DDI2, the lab aims to improve the survival rates and treatment outcomes for cancer patients.