Dr. Zhaohui Feng's lab at Rutgers focuses on understanding colorectal cancer, particularly the role of a protein called Parkin in cancer progression. Parkin is often downregulated in colorectal cancer, and the lab aims to explore how this affects cancer development and how it can be targeted for therapy. Their research combines advanced screening methods and mouse models to uncover new treatment strategies for colorectal cancer, especially in cases where Parkin is deficient.

Dr. Zhiyuan Shen's lab focuses on understanding the mechanisms by which BRCA proteins help maintain DNA integrity and influence cancer therapy. The team investigates how deficiencies in DNA repair processes contribute to cancer and how we might exploit these defects for treatment. Their research aims to improve outcomes for patients with BRCA-related cancers, such as breast cancer and medulloblastoma.