Hui Zhang · Chemistry
Dr. Hui Zhang's lab at the University of Nevada Las Vegas focuses on understanding how specific proteins are modified by the addition of methyl groups to lysine residues, which can lead to their targeted destruction in the cell. This research is important because it links protein modification to various biological processes, including the regulation of stem cells and the development of cancers. By exploring the mechanisms behind this process, the lab aims to provide insights that could lead to new treatments for diseases associated with these pathways.
Ernesto V Abel-Santos · Chemistry
Dr. Ernesto V Abel-Santos leads research at the University of Nevada Las Vegas focused on combating Clostridium difficile infections (CDI). His lab investigates innovative bile salt analogs that can inhibit the germination of C. difficile spores without causing toxicity. By synthesizing and testing these compounds, the lab aims to develop safe prophylactic treatments to reduce CDI incidence, addressing a significant public health concern.