Dr. Helen Zgurskaya's lab focuses on understanding how certain bacteria, particularly those that cause serious infections like tuberculosis and gram-negative pathogens, transport lipids and drugs in their cells. By studying unique proteins and their structures, the lab aims to uncover mechanisms behind bacterial resistance to antibiotics and to develop new therapeutic approaches. The research combines diverse disciplines, including biochemistry, microbiology, and machine learning, to provide insights that can lead to the discovery of novel antibiotics.