Dr. Jianfeng Cai's lab at the University of South Florida focuses on understanding Alzheimer's disease, specifically how amyloid beta peptides aggregate in the brain and contribute to dementia. The lab is creating new molecules that can prevent and disrupt this aggregation, potentially leading to effective treatments. Their research combines chemistry, biology, and innovative material design to develop therapeutic agents that may help improve memory and brain function in patients with Alzheimer's.

Dr. Henry Lee Woodcock III's lab at the University of South Florida focuses on developing advanced computational methods to study biomolecular systems. By creating new techniques for hybrid quantum mechanical/molecular mechanical (QM/MM) simulations, the lab aims to solve complex biochemistry problems related to drug targets in pathogenic bacteria and strategies to combat antimicrobial resistance. This research is crucial for understanding how enzymes work and for developing new treatments for diseases.