Matthew J Allen · Chemistry
Dr. Matthew Allen's lab focuses on developing innovative imaging agents that can help visualize oxygen levels in the body, which is crucial for understanding diseases like cancer and kidney disorders. The lab is working on a new class of contrast agents that contain europium, a rare earth element, aiming to improve their delivery and effectiveness in medical imaging. This research has the potential to transform diagnostics and therapy for conditions associated with low oxygen levels.
Hien M Nguyen · Chemistry
Dr. Hien M Nguyen's lab at Wayne State University focuses on synthesizing complex carbohydrate structures to improve medical treatments and vaccines. They are actively developing new methods for creating glycosylations, which are crucial for producing compounds that can support cancer treatments and vaccine efficiency. The lab's research aims to better understand biologically important molecules and to enhance immune responses against diseases through innovative vaccine adjuvants.
Mary Kay H Pflum · Chemistry
Dr. Mary Kay Pflum's lab at Wayne State University focuses on understanding how modifications to proteins, such as phosphorylation and acetylation, influence their function and interactions in cells. These modifications are crucial for many cellular processes and are linked to diseases like cancer. The lab develops innovative chemical tools to study these protein changes, which could help in discovering new disease mechanisms and treatments.