Dr. Bruce Korf's lab at the University of Alabama at Birmingham focuses on diagnosing rare and chronic diseases in patients who have not been able to find answers through traditional medical avenues. The lab employs advanced genetics techniques, including genome sequencing, to identify underlying causes of these conditions. They also leverage innovative tools like artificial intelligence and telemedicine to enhance diagnostic efficiency and broaden access to necessary evaluations.

Dr. William M Marsiglia's lab focuses on understanding how a key protein called AKT becomes activated and interacts with other proteins in both healthy and diseased cells. They use advanced imaging techniques to visualize these processes in real time, which can provide insights into diseases and help identify new treatment targets. The research aims to enhance our understanding of cellular functions related to growth and metabolism and how they are impacted by various diseases.

Dr. Deeann Wallis-Schultz's lab at the University of Alabama at Birmingham focuses on understanding how a gene called NF1 contributes to breast cancer development, particularly in hormone-sensitive cases. The lab utilizes innovative rat models that mimic human breast cancer to study how loss of this gene affects tumor growth and response to treatments. The ultimate goal is to improve cancer prognosis and develop new therapies for patients with specific NF1 mutations.