The lab led by Dr. Laurence Morel focuses on understanding systemic lupus erythematosus (SLE), an autoimmune disease characterized by inappropriate immune responses. They investigate how specific cells in the immune system, particularly follicular helper T cells, contribute to the disease, and explore the effects of gut bacteria on immune function and disease severity. By studying the interaction between metabolism and immune response, the lab aims to find potential treatments to alleviate lupus symptoms through dietary and pharmacological interventions.

Dr. Daniel James Salamango's lab explores the mechanisms behind HIV persistence, particularly focusing on how the HIV protein Vpr affects myeloid cells, like macrophages. They aim to understand how Vpr-induced changes in the cell's genetic material can help the virus survive in these cells, which could lead to new treatments for HIV. The findings could also contribute to the broader goal of finding a cure for HIV infection.