Dr. Deepta Bhattacharya's research lab focuses on understanding the molecular mechanisms behind antibody responses and immunity. They investigate how specific metabolic pathways influence the lifespan and function of plasma cells, which are crucial for long-term immune protection. By using advanced genetic tools and various experimental models, the lab aims to uncover the cellular and metabolic factors that determine how long antibodies remain effective after vaccination or infection.

Dr. Janko Z. Nikolich's lab focuses on understanding how aging affects the immune system, particularly the decline of T cells in older adults. By investigating the mechanisms behind this decline, the lab aims to develop strategies for rejuvenating T cells to improve health and immunity in the elderly. They also explore how cytomegalovirus (CMV) influences aging in people living with HIV, with the goal of establishing better treatments for age-related conditions in this population.