Dr. Robert Benjamin Levy's lab at the University of Miami School of Medicine focuses on improving outcomes for corneal transplants by manipulating the immune system. The research aims to induce long-lasting immune tolerance to prevent transplant rejection, particularly in high-risk patients. By studying regulatory T cells and using innovative therapies, the lab seeks to develop new strategies to maintain corneal clarity and enhance the success of corneal transplantation.

Dr. Daniela Frasca's research focuses on understanding how aging and HIV affect the immune system, specifically looking at the metabolic changes that occur in immune cells. The lab studies how these changes can lead to poorer immune responses and aims to develop strategies to improve immunity in aging individuals living with HIV. By exploring the links between metabolism, inflammation, and immune function, this research could help enhance the health of older adults with HIV.

Dr. Shembade's lab at the University of Miami focuses on understanding Kaposi's sarcoma, a cancer associated with HIV/AIDS, and the complex interactions between HIV and the Kaposi's sarcoma herpesvirus (KSHV). The lab develops innovative mouse and cell models that mimic disease conditions, allowing for the testing of new therapeutic strategies aimed at improving treatment for affected populations. By conducting research in these models, the lab aims to unravel the mechanisms of viral oncogenesis and to advance the development of immunological therapies against this malignancy.

Dr. Erietta Stelekati's lab at the University of Miami focuses on understanding how certain immune cells, specifically CD8 T cells, become dysfunctional during chronic infections and cancer. The lab studies the role of microRNAs, particularly miR-29a, in regulating these cells' ability to react to cancer treatments. By exploring how miR-29a affects the genetic drivers of T cell exhaustion, the lab aims to uncover new strategies to enhance the effectiveness of immunotherapies.