Dr. Momoko Yoshimoto's research focuses on understanding how different types of B cells develop from various origins during fetal development and their significance in health and disease. Her lab explores the developmental pathways of B cells that arise independently of hematopoietic stem cells, which challenges traditional views in immunology. By using advanced mouse models, the lab aims to uncover the functional differences between these newly identified B cell subsets and their counterparts derived from the bone marrow.