Dr. Yongjie Yang's lab at Tufts University studies the role of glial cells in neurodevelopmental and neurodegenerative diseases. Specifically, they investigate how astrocytes, a type of glial cell, contribute to conditions like Fragile X Syndrome and Alzheimer's Disease. The research focuses on understanding the molecular mechanisms influencing behavior and immune responses in these diseases.

Dr. Chris G. Dulla's lab at Tufts University focuses on understanding how astrocytes, a type of brain cell, change as we age and in conditions like Alzheimer’s Disease (AD). The lab has identified a new type of astrocyte called atypical astrocytes (AtAs) that lose important functions, which might contribute to neurological issues. They are exploring how vascular health and blood-brain barrier integrity relate to these changes and how they affect overall brain function during aging and disease.

Dr. Stephen J. Moss's lab at Tufts University focuses on understanding how neuroactive steroids affect brain function, particularly through a family of receptors known as G-protein coupled receptors. These steroids can influence behavior and may offer new treatments for mental health issues like postpartum depression. The lab uses various techniques to explore how these compounds mediate their effects on neuronal excitability and might lead to innovative strategies for improving mental health.

Dr. Maribel Rios' lab studies how specific brain signals affect our body's energy and glucose management. Particularly, they focus on the relationship between two proteins, thrombospondin and a2d-1, in the brain regions that control eating and metabolism. By understanding how these proteins work, the lab hopes to find new ways to treat obesity and related metabolic diseases.