Dr. Hussein N. Yassine's lab focuses on understanding the links between type II diabetes, Alzheimer's disease, and cognitive decline, particularly within Latino communities at higher risk for these conditions. The lab works on both understanding brain health through imaging and developing new drugs aimed at reducing neuroinflammation associated with Alzheimer's. By studying brain mechanics and pharmaceutical interventions, the team aims to identify effective strategies to mitigate cognitive decline in vulnerable populations.

Dr. Jeiran Choupan's lab at the University of Southern California focuses on understanding the brain's perivascular spaces (PVS) and their role in aging and Alzheimer's disease (AD). This research aims to map the structure and diffusion properties of PVS in the brain, helping to uncover how they change with age and in conditions like AD. By using advanced imaging techniques, the lab hopes to develop resources that other researchers can use to study neurological disorders related to PVS dysfunction.

Dr. Danny Jj Wang's lab at the University of Southern California focuses on understanding how small vessel disease affects cognitive function and dementia through innovative imaging techniques. They are working to validate biomarkers that help identify these conditions, with a specific emphasis on diverse populations in Los Angeles. The lab is also exploring how the blood-brain barrier functions and can be assessed non-invasively using MRI technology, which could lead to new diagnostic tools for neurodegenerative diseases.

Dr. Neda Jahanshad's lab at the University of Southern California focuses on understanding the brain's white matter circuitry, which is essential for communication between neurons. The lab collaborates with the ENIGMA consortium to perform large-scale studies that link genetic factors to variations in white matter associated with severe mental illnesses like schizophrenia and depression. Through sophisticated neuroimaging techniques and data integration tools, the lab aims to advance our knowledge of how brain structure relates to mental health conditions and offers publicly accessible platforms for other researchers.