Dr. Jagdish Singh's lab focuses on developing new therapies for Alzheimer's Disease, a common neurodegenerative disorder. The lab is particularly interested in using gene therapy to increase levels of certain proteins, like APOE2 and VGF, that may protect brain function and improve cognitive abilities. They create specialized nanoparticles to deliver these therapeutic genes across the blood-brain barrier, aiming to enhance the effectiveness of treatments for Alzheimer's and related conditions.