Dr. Gabrielle Rudenko's lab at the University of Texas Medical Branch focuses on studying synaptic organizers, which are important proteins that help strengthen connections between neurons in the brain. The lab investigates how these proteins, especially a group called neurexins, function and regulate their interactions, which can lead to better understanding of neuropsychiatric disorders like schizophrenia and autism. By exploring the mechanisms behind these interactions, the lab aims to find new therapeutic approaches to treat severe mental illnesses that affect millions.

Dr. Jia Zhou's lab at the University of Texas Medical Branch Galveston focuses on understanding cocaine use disorder (CUD) and exploring new treatments. The team is particularly interested in how serotonin receptors can be modulated to help reduce cravings and relapse in individuals struggling with CUD. They aim to develop novel compounds that improve serotonin receptor function as a potential therapy for CUD and related neuropsychiatric disorders.

Dr. Fernanda Laezza's lab focuses on understanding and treating psychiatric disorders by investigating brain circuits and their behaviors. The research emphasizes developing novel chemical probes that target specific protein interactions in neurons, particularly related to reward mechanisms. By studying how these probes influence neuronal activity, the team aims to uncover new therapeutic strategies for various mental health conditions.