Dr. Adam Steven Smith's lab at the University of Kansas Lawrence focuses on understanding the effects of social loss on the brain, particularly in the context of losing a partner. Using a prairie vole model, the lab investigates how such losses impact emotional and motivational states, aiming to uncover the neurobiological mechanisms behind prolonged grief and develop potential therapeutic interventions. The research combines behavioral studies with neuroscience to provide insights into the brain's response to emotional trauma related to social connections.

Dr. Jaichandar Subramanian's research lab focuses on understanding Alzheimer's disease, particularly how changes in neuronal activity and synaptic function relate to mitochondrial health. By studying mouse models of the disease, the lab aims to uncover how these factors interact across different ages and brain regions. Ultimately, the goal is to find ways to improve cognitive function by restoring normal brain activity and synapse structure.

Dr. Michael S. Wolfe's lab at the University of Kansas focuses on understanding the mechanisms of Alzheimer's disease, particularly how a key enzyme called gamma-secretase processes amyloid precursor proteins. The lab investigates both genetic mutations that lead to familial Alzheimer's disease and broader factors that influence neuron degeneration. By exploring these processes, the team aims to discover new treatment strategies that might benefit individuals suffering from Alzheimer's, especially those with the late-onset form of the disease.