Kenneth P Wright · Physiology
Dr. Kenneth P. Wright's lab at the University of Colorado focuses on understanding circadian rhythms, particularly how disruptions can lead to sleep disorders like Delayed Sleep-Wake Phase Disorder (DSWPD). The research aims to identify biomarkers for circadian rhythms in peripheral tissues and develop new treatment strategies to improve health and daily functioning for affected individuals.
Christopher D. Link · Physiology
Dr. Christopher D. Link's lab at the University of Colorado focuses on understanding the role of double-stranded RNA in the cell death associated with Alzheimer's disease and related neurodegenerative diseases like ALS and Frontotemporal Dementia. The lab investigates how this RNA accumulates in neurons and glial cells, leading to neuroinflammation and neuronal dysfunction. The goal is to uncover new therapeutic targets to combat these currently untreatable diseases.
Douglas R Seals · Physiology
Dr. Douglas R. Seals' lab focuses on understanding how lifestyle interventions, like heat therapy and inspiratory muscle strength training, can improve cardiovascular health, particularly in mid-life and older adults. They investigate how these methods can lower high blood pressure and enhance blood vessel function, helping to mitigate risks for heart disease and other age-related issues. The research aims to explore both the effectiveness of these interventions and the underlying biological mechanisms involved.