Dr. Albert Gonzales' lab at the University of Nevada Reno focuses on understanding how certain brain cells, called pericytes, regulate blood flow in tiny blood vessels called capillaries, and how this process is affected in Alzheimer's disease. The research explores how amyloid-beta proteins disrupt the normal functions of pericytes, which could lead to cognitive decline in aging individuals. By studying these mechanisms, the lab aims to identify potential therapeutic strategies for improving brain health and preventing neurodegeneration associated with Alzheimer's and other vascular diseases.

Dr. Sal Baker's lab at the University of Nevada Reno studies how specific cells in the colon, called interstitial cells of Cajal (ICC), help control gut movement. They are exploring how these cells interact with smooth muscle and nerves to regulate contractions in the intestines, which is important for understanding disorders like constipation. The goal is to uncover new regulatory mechanisms that could lead to better treatments for gastrointestinal motility issues.

Dr. Sean Ward's lab at the University of Nevada Reno focuses on understanding how human stomach muscles work, specifically why some people have trouble with stomach function. They investigate the electrical signals that help the stomach move food through the digestive system and how factors like age, gender, and genetics affect these processes. By studying human tissues directly, the lab aims to uncover new insights that can lead to better treatments for conditions like gastroparesis and dyspepsia.