Dr. Jennifer Wootton Hill's lab studies how brain cells called astrocytes influence fertility and puberty by sensing insulin levels. They focus on the mechanisms that link energy availability to reproductive functions, especially how astrocytes help control the release of hormones essential for reproduction. The research aims to find treatments for infertility related to metabolic disorders such as obesity and diabetes.

Dr. Bina Joe's lab at the University of Toledo focuses on understanding the role of gut microbiota in hypertension, a leading cause of cardiovascular disease. The lab investigates how specific gut bacteria influence the levels of conjugated bile acids, which may have protective effects against high blood pressure. By using advanced rodent models, the team aims to uncover the biochemical mechanisms involved and explore new therapeutic approaches to lower hypertension through dietary interventions.

Dr. Sailaja Paruchuri's lab at the University of Toledo focuses on understanding how specific receptors in lung cells influence inflammation, particularly in conditions like asthma and acute lung injury. The lab investigates the role of cysteinyl leukotriene receptors and their impact on macrophage behavior, which are essential immune cells in the body. By studying these mechanisms, the lab aims to develop new therapeutic strategies for treating lung inflammation and related diseases.