Robijanto Soetedjo · Physiology
Dr. Robijanto Soetedjo's lab at the University of Washington studies how the cerebellum processes signals that control eye movements known as saccades. By examining the neural circuits involved in these movements, particularly how specific cells contribute to their timing and direction, the lab aims to uncover fundamental insights into motor control. This research could lead to improved rehabilitation strategies for people with movement disorders.
Sharona E Gordon · Physiology
Dr. Sharona E. Gordon's lab at the University of Washington focuses on understanding how nerve growth factor (NGF) influences the behavior of TRPV1 ion channels, which are important for pain sensation. By employing innovative chemical biology techniques, the lab studies how NGF regulates the movement of TRPV1 channels to the cell membrane in response to inflammation. This research could identify new targets for pain management therapies.
Jeansok John Kim · Physiology
Dr. Jeansok John Kim's lab at the University of Washington focuses on understanding how animals, particularly rodents, process fear and make decisions in the face of threats. The research investigates the brain pathways that govern fear responses, especially in realistic environments where dangers can be ambiguous. By studying these neural dynamics, the lab aims to inform better treatments for trauma-related disorders in humans.
John Tuthill · Physiology
Dr. John Tuthill's lab at the University of Washington focuses on understanding how proprioceptive sensors help animals detect the limits of joint movement and control locomotion. By studying the fruit fly, Drosophila, the lab aims to reveal the neural mechanisms involved in sensorimotor control. This research is important for improving our understanding of sensorimotor disorders and may lead to better treatments.
Steve I Perlmutter · Physiology
Dr. Steve I. Perlmutter's laboratory focuses on improving recovery from spinal cord injuries using a novel neuroprosthetic therapy. The lab explores the use of targeted spinal stimulation to enhance movement in individuals who have suffered from cervical spinal cord injuries. By investigating the body's natural ability to adapt and recover neural functions, the lab aims to develop more effective rehabilitation methods and prepare for future clinical applications.
Charles L Asbury · Physiology
Dr. Charles L. Asbury's lab at the University of Washington studies how the mitotic spindle, a complex molecular machine, separates chromosomes during cell division. By using purified components and advanced biophysical tools, they investigate the mechanics of the spindle and kinetochores, uncovering how these structures ensure accurate chromosome segregation. Their research aims to deepen our understanding of cellular processes, with implications for developing new cancer treatments.