Ulrike Klueh · Physiology
Dr. Ulrike Klueh's lab focuses on developing innovative technologies to improve insulin delivery systems for diabetes management. They aim to enhance the longevity and effectiveness of insulin infusion pumps by addressing the inflammatory reactions caused by preservatives in insulin. Their research combines biomedical engineering and physiology to create solutions that alleviate tissue damage from subcutaneous insulin administration, thus aiming to improve the quality of life for diabetes patients.
Pablo A. Ortiz · Physiology
Dr. Pablo A. Ortiz's lab at Wayne State University focuses on understanding how proteins interact with the kidney's sodium chloride transporter, NKCC2, which plays a key role in regulating salt balance and blood pressure. Their research investigates the molecular mechanisms behind sodium reabsorption and explores the functions of proteins ALMS1 and ACTN4 in relation to hypertension and renal health. By studying these interactions, the lab aims to uncover new insights into kidney function and related diseases.
Zhibing Zhang · Physiology
Dr. Zhibing Zhang's lab at Wayne State University focuses on understanding the development and functioning of sperm cells, with an emphasis on the mechanisms involved in spermiogenesis and fertilization. They investigate how specific proteins and complexes, like the MEIG1 complex and the IFT25/IFT27 complex, contribute to the formation of sperm flagella and the remodeling of chromatin, which is crucial for normal reproductive processes.