Dr. Lori A. Knackstedt's lab at the University of Florida focuses on understanding the effects of combining opioid and alcohol use, known as polysubstance use. This research is particularly important because it looks at how this combination worsens cognitive functions and health outcomes. By studying human behavior and creating rodent models, the lab aims to uncover the underlying mechanisms that lead to addiction and impaired cognition, which could help develop better treatments and interventions for substance use disorders.