Dr. Deanna Barch's lab focuses on understanding the reasons behind motivational impairments in individuals with psychotic and mood disorders. The research aims to investigate how these impairments affect decision-making related to effort and rewards in everyday life. By employing innovative behavioral assessments and neuroimaging techniques, the lab seeks to differentiate the mechanisms of motivation between individuals with psychosis, like schizophrenia and bipolar disorder, and those with depression.

Dr. Zachariah Meadows Reagh's research lab at Washington University focuses on understanding how aging, particularly in individuals at risk for Alzheimer's disease, affects memory. The lab explores the nuances of episodic memory, including how different features of memories are impacted by aging, and how these changes relate to brain network dysfunction. Through innovative behavioral tests and advanced imaging techniques, the lab aims to make significant contributions to our understanding of memory decline and to inform future clinical assessments and treatments.