Dr. Hani Zaher's lab at Washington University studies how cells respond to stress by examining the ribosome's role in managing and repairing RNA during damage. They explore how ribosomes signal for quality control and stress responses, helping to maintain cellular health. Their research aims to better understand how these mechanisms support cellular functions and protect against diseases like cancer and neurodegeneration.

Dr. Guoyan Zhao's lab at Washington University focuses on understanding Lewy body diseases, including Parkinson's disease and related forms of dementia. The research examines how certain neurons and brain regions are uniquely vulnerable to damage in these disorders, using advanced genomic tools and bioinformatics. By identifying molecular mechanisms and biomarkers, the lab aims to develop targeted strategies for therapy and diagnosis.