Brown University · BiochemistryNeurodevelopmental Genetics Lab
Eric M Morrow · Providence, Rhode Island
Research Focus
Dr. Eric Morrow's lab at Brown University investigates the biological mechanisms behind neurodevelopmental and neurodegenerative disorders. The research focuses on genetic factors, particularly copy number variations (CNVs), that increase the risk of conditions like autism. By studying animal models and human stem cells, the lab seeks to understand how these genetic changes affect brain development and neuronal health, with the goal of developing new therapeutic strategies.
neurodevelopmentcopy number variationsautismneurodegenerationmetabolismlocus coeruleusstem cellstherapeuticsbrain disordersgenetics
Research Aims
4AIM 01Investigate neurodevelopmental mechanisms related to autism caused by 17q12 CNVs.
AIM 02Examine metabolic pathways contributing to locus coeruleus neuron vulnerability in neurodegenerative diseases.
AIM 03Assess rescue strategies for 17q12 CNV neurons derived from human stem cells.
AIM 04Identify predictive biomarkers of neuron health in models of Alzheimer's disease.
Skills the Lab Values
animal modelscell cultureRNA sequencingCRISPRWestern blottranscriptional profilingbehavioral assaysmetabolomicsMRI imaginggenetic engineering
Output against the department
Publications150bottom 42% of dept.235th of 402
this lab
most publishedleast published
Citations15ktop 30% of dept.122nd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.