University of California-San Diego · Chemistry · BiologyAI and Molecular Biology Innovations Lab
Wei Wang · La Jolla, California
Research Focus
Dr. Wei Wang’s lab at UC San Diego focuses on cutting-edge research combining artificial intelligence and molecular biology to explore innovative solutions for anti-aging therapies and genetic disease. The first major project aims to develop advanced AI models for designing antibodies that can rejuvenate the immune system, ultimately improving life quality in aging populations. The second project investigates the role of non-coding DNA regions in cellular functions and disease, aiming to uncover how mutations in these regions affect health and could lead to new therapeutic approaches.
AI modelsanti-agingantibody designnon-coding regionscell viabilitygenome editingchromatin organizationepigeneticsdisease mechanisms
Research Aims
5AIM 01Develop AI models for antibody design to improve immune system rejuvenation.
AIM 02Generate diverse antibody-antigen interactions to train models for better prediction accuracy.
AIM 03Evaluate the performance of new AI models for optimizing antibody properties.
AIM 04Identify non-coding DNA regions crucial for cell survival and characterize their functions.
AIM 05Investigate the impact of mutations in non-coding regions on chromatin organization and disease.
Skills the Lab Values
AI model trainingCRISPR library screeningHi-C analysissingle-cell RNA sequencingATAC-seqin vitro assaysdata analysismolecular cloningantibody affinity testing
Output against the department
Publications2,470top 1% of dept.2nd of 1,248
this lab
most publishedleast published
Citations77ktop 2% of dept.19th of 1,248
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.