Northwestern University · PharmacologyBurridge Cardiotoxicity Lab
Paul W. Burridge · Evanston, Illinois
Research Focus
Dr. Paul W. Burridge's lab at Northwestern University focuses on understanding and preventing heart and vascular problems in children and adults receiving cancer treatments. They use advanced techniques like human stem cells to study genetic factors that contribute to heart issues caused by chemotherapy and newer cancer therapies. Their goal is to create tools that help predict and prevent these adverse effects, particularly in underserved populations, like African American survivors of childhood cancers.
cardiotoxicitycancer treatmenthuman induced pluripotent stem cellsgenomic researchvascular disease
Research Aims
5AIM 01Identify genetic variants associated with chemotherapy-induced heart problems in children
AIM 02Develop predictive models for adverse drug reactions in cancer patients
AIM 03Validate mechanisms of vascular disease linked to cancer therapies
AIM 04Generate patient-specific stem cells to study drug responses
AIM 05Create tools for personalized medicine in managing cancer treatments.
Skills the Lab Values
cell cultureRNA sequencingCRISPRgenome editinggenomic analysisphenotypic assaysbiochemical assaysdata analysispatient recruitmentclinical trial design
Output against the department
Publications152bottom 42% of dept.266th of 462
this lab
most publishedleast published
Citations9.9ktop 38% of dept.176th of 462
this lab
most citedleast cited
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