Harvard University · Microbiology & ImmunologyGarrett Microbiome Lab
Wendy S. Garrett · Cambridge, Massachusetts
Research Focus
Dr. Wendy S. Garrett's lab at Harvard University focuses on understanding the role of the gut microbiome, particularly the bacterium Fusobacterium nucleatum, in colorectal cancer (CRC). The team investigates how specific bacterial activities contribute to CRC progression, response to therapy, and overall cancer susceptibility. By exploring the interactions between F. nucleatum and immune cells, the lab aims to uncover mechanisms that may apply to various cancers beyond CRC.
colorectal cancerFusobacterium nucleatumgut microbiomecarcinogenesisimmunology
Research Aims
5AIM 01Analyze the role of Fusobacterium nucleatum in colorectal carcinogenesis.
AIM 02Investigate specific metabolic byproducts of Fusobacterium nucleatum that affect cancer progression.
AIM 03Examine F. nucleatum interactions with immune cells in the tumor microenvironment.
AIM 04Identify potential therapeutic targets related to Fusobacterium nucleatum.
AIM 05Explore the broader implications of gut microbiome interactions in cancer beyond colorectal cancer.
Skills the Lab Values
PCRcell culturemouse modelsimmunohistochemistryRNA sequencing
Output against the department
Publications271top 20% of dept.95th of 486
this lab
most publishedleast published
Citations65ktop 2% of dept.11th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.