Yale University · BiologyThe Aging Dynamics Lab
Vishwa Deep Dixit · New Haven, Connecticut
Research Focus
Dr. Vishwa Deep Dixit's lab focuses on understanding how aging and inflammation are linked to chronic diseases. By investigating the role of Fibroblast Growth Factor 21 (FGF21) and its receptor Klotho, the lab aims to uncover new strategies to enhance healthspan and lifespan by reducing age-related inflammation and metabolic dysfunction. The research includes exploring how FGF21 can be used therapeutically to combat the effects of aging.
aginginflammationFGF21healthspanmetabolismchronic diseasegerontologyimmune-senescenceneural circuits
Research Aims
5AIM 01Investigate the role of FGF21 in reducing immune-senescence.
AIM 02Explore mechanisms by which FGF21 influences energy metabolism.
AIM 03Develop pharmacological strategies to enhance FGF21 signaling.
AIM 04Examine the relationship between aging, inflammation, and chronic disease.
AIM 05Utilize mouse models to test FGF21 as a potential therapy for longevity.
Skills the Lab Values
cell culturemouse modelsgenetic engineeringbiochemical assaysin vivo imagingCytokine assaysWestern blotRNA sequencingflow cytometry
Output against the department
Publications158top 42% of dept.437th of 1,033
this lab
most publishedleast published
Citations18ktop 22% of dept.230th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.