Wayne State University · PharmacologyLiver Metal Interaction Lab
Wanqing Liu · Detroit, Michigan
Research Focus
Dr. Wanqing Liu's lab at Wayne State University focuses on understanding how heavy metals interact with our genes and how these interactions may contribute to nonalcoholic fatty liver disease (NAFLD). They investigate how metal exposure affects liver cells and the overall health of the liver, aiming to provide insights that could lead to new diagnostics and treatments for liver diseases. Their work combines advanced techniques in genomics and bioinformatics to analyze human liver tissues and patient data.
nonalcoholic fatty liver diseasegene-environment interactionsheavy metalsgene expressionmulti-omicsliver healthbioinformaticssingle cell RNA-seqATAC-seq
Research Aims
3AIM 01Profile heavy metals in human liver tissues and assess their relationship with NAFLD.
AIM 02Investigate how different liver cell populations respond to metal exposure using advanced sequencing techniques.
AIM 03Validate the impact of gene-heavy metal interactions on the severity of NAFLD in a large patient cohort.
Skills the Lab Values
RNA sequencingsingle cell analysisATAC-seqbioinformaticscell culturehuman tissue collectionstatistical analysisdata visualization
Output against the department
Publications632top 6% of dept.27th of 462
this lab
most publishedleast published
Citations52ktop 5% of dept.21st of 462
this lab
most citedleast cited
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