University of Florida · NeuroscienceRumbaugh Lab
Gavin R Rumbaugh · Gainesville, Florida
Research Focus
Dr. Gavin R Rumbaugh's lab at the University of Florida focuses on understanding how genetic factors influence brain development and behavior, particularly in the context of neurodevelopmental disorders. The lab investigates how genes associated with disorders like autism and schizophrenia affect the structure and function of circuits in the brain, which are critical for cognitive processing and behavior. Their research uses mouse models to uncover the relationships between gene expression, neural circuit assembly, and behavioral outcomes.
neurodevelopmental disorderscognitive functionbrain circuitsgenetic risk factorsmouse modelssynaptic plasticitydendritic morphogenesistouch perceptionbehavioral adaptations
Research Aims
3AIM 01Investigate how Syngap1 expression in cortical neurons affects tactile learning and behavior in mice.
AIM 02Analyze how Syngap1 regulates cortical plasticity during sensory learning tasks.
AIM 03Examine the role of Syngap1 in modulating arousal centers relevant to learning and behavior.
Skills the Lab Values
PCRcell culturemouse modelsbehavioral phenotypingimmunohistochemistrygenetic manipulationelectrophysiologydendritic morphology analysisdata analysis
Output against the department
Publications114bottom 40% of dept.401st of 671
this lab
most publishedleast published
Citations9.1ktop 43% of dept.290th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.