RUThe Rockefeller University · Chemistry
Cell Division Dynamics Lab
Tarun M. Kapoor · New York, New York
Research Focus
Dr. Tarun M. Kapoor's lab at Rockefeller University focuses on understanding the crucial molecular processes that allow cells to divide correctly. Mistakes in cell division can lead to serious diseases, including cancer. The research combines chemical biology and advanced microscopy techniques to investigate how different proteins and structures contribute to this dynamic process. The aim is to discover new insights that may lead to innovative treatments for diseases caused by cell division errors.
cell divisioncancermicrotubulesprotein-protein interactionschemical biologycell biologytherapeuticsstructural biology
Research Aims
5AIM 01Identify the functions of AAA mechanoenzymes during cell division.
AIM 02Characterize the structural basis of microtubule nucleation by the g-TuRC complex.
AIM 03Develop chemical probes to manipulate protein functions in living cells.
AIM 04Examine the dynamics of microtubule formation and organization during mitosis.
AIM 05Investigate transient protein-protein interactions in the context of cell division.
Skills the Lab Values
cell culturelattice light-sheet microscopychemical proteomicsquantitative image analysisrecombinant protein expressiondrug screeningbiochemical assaysmicroscopy techniquesprotein purification
Output against the department
Publications244top 46% of dept.99th of 216
this lab
most publishedleast published
Citations16ktop 30% of dept.65th of 216
this lab
most citedleast cited
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