University of Chicago · Biomedical EngineeringCarroll Stroke Lab
Timothy J Carroll · Chicago, Illinois
Research Focus
Dr. Timothy J Carroll's lab at the University of Chicago focuses on developing innovative treatments for acute ischemic strokes. The lab is investigating a novel synthetic blood substitute called Sanguinate, which aims to improve blood flow and oxygen delivery to the brain during a stroke. By enhancing collateral blood vessel growth and providing targeted oxygen release, the research seeks to minimize brain damage and improve patient outcomes during emergencies.
ischemic strokeblood substituteoxygen deliverycollateralizationbrain infarctionvascular healthbiopharmaceuticalsreperfusion injurystroke treatment
Research Aims
4AIM 01Test the efficacy of the Sanguinate blood substitute in reducing infarct growth during ischemic strokes.
AIM 02Evaluate the mechanism of action of Sanguinate in enhancing oxygen delivery and reducing inflammation.
AIM 03Establish protocols for administering the new treatment in emergency medical settings.
AIM 04Investigate the safety and potential of Sanguinate in human clinical trials.
Skills the Lab Values
animal modelsimaging techniquesbiomarker analysisdrug delivery systemsemergency department protocolsclinical trial designbioinformaticsdata collectionpharmacology
Output against the department
Publications223top 47% of dept.274th of 595
this lab
most publishedleast published
Citations8.3ktop 40% of dept.239th of 595
this lab
most citedleast cited
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