Harvard University · BiologyAuditory Nexus Lab
Lisa Goodrich · Cambridge, Massachusetts
Research Focus
Lisa Goodrich's lab at Harvard Medical School studies how specialized cells in the cochlea, particularly glia and neurons, interact to support hearing throughout life. Her team investigates the genetic and molecular mechanisms behind these interactions and how they may be disrupted in conditions leading to hearing loss. By exploring these relationships, they aim to uncover methods to promote recovery from cochlear damage and better understand auditory function.
cochlear gliaspiral ganglion neuronsauditory circuit assemblyhearing lossmolecular mechanisms
Research Aims
3AIM 01Investigate the developmental role of cochlear glia in supporting auditory circuit formation.
AIM 02Characterize how transcription factors Gata2 and Gata3 influence neuron-glia interactions.
AIM 03Define the molecular basis of synaptic heterogeneity in spiral ganglion neurons.
Skills the Lab Values
molecular geneticsmouse modelsCRISPRRNA sequencingimmunohistochemistrytime-lapse imaginggene expression analysiscell culturescRNA-sequencing
Output against the department
Publications117bottom 42% of dept.598th of 1,033
this lab
most publishedleast published
Citations11ktop 33% of dept.344th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.