Yale University · Microbiology & ImmunologyGalan Lab
Jorge E Galan · New Haven, Connecticut
Research Focus
Dr. Jorge E. Galan's research lab at Yale University focuses on understanding how the bacterium Salmonella affects host cells. By studying the ways that Salmonella uses specific proteins to manipulate cellular functions, the lab aims to uncover the secrets of how the bacteria survive and cause disease. This research could lead to new treatments and preventions for Salmonella infections, which pose a significant public health threat. The team investigates cellular signaling pathways and immune responses to advance our knowledge of host-pathogen interactions.
Salmonellahost-pathogen interactionstype III secretion systemintestinal inflammationcell signaling pathways
Research Aims
5AIM 01Investigate how Salmonella uses its effectors to manipulate host cell functions.
AIM 02Examine the immune responses triggered by Salmonella infections.
AIM 03Study the mechanisms of intestinal inflammation caused by Salmonella.
AIM 04Understand the biochemical activities of Salmonella effector proteins.
AIM 05Explore host defense pathways that regulate Salmonella replication.
Skills the Lab Values
cell culturemouse modelsPCRWestern blotimmunofluorescence microscopy
Output against the department
Publications250top 22% of dept.109th of 486
this lab
most publishedleast published
Citations36ktop 8% of dept.37th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.