Stanford University · BiologyVilleneuve Lab
Anne M Villeneuve · Stanford, California
Research Focus
Dr. Anne M Villeneuve's lab focuses on how chromosomes are accurately divided during the process of meiosis, which is essential for producing healthy eggs and sperm. By studying a small roundworm called Caenorhabditis elegans, the lab aims to uncover the important molecular and cellular processes that ensure chromosomes are inherited correctly. This research is crucial because mistakes in chromosome segregation can lead to miscarriages, birth defects, and even cancer.
meiosischromosome inheritanceC. elegansgenome integrityDNA repairmeiotic recombinationchromosomal organizationaneuploidygamete formationSpontaneous abortion
Research Aims
4AIM 01Elucidate mechanisms ensuring reliable formation of crossover connections between chromosomes.
AIM 02Explore coordination of meiotic events and transitions at temporal and spatial levels.
AIM 03Investigate chromosome structures crucial for regulating meiotic recombination.
AIM 04Understand how homolog recognition is fundamentally achieved during meiosis.
Skills the Lab Values
cell culturegenetic manipulationmicroscopyDNA sequencingbiochemical assayschromosome mappinghybridization techniquesdata analysisquantitative genetics
Output against the department
Publications108bottom 37% of dept.641st of 1,033
this lab
most publishedleast published
Citations9.1ktop 42% of dept.430th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.