University of North Carolina at Chapel Hill · PhysiologyCilia Neurobiology Unit
Eva S Anton · Chapel Hill, North Carolina
Research Focus
Dr. Eva S. Anton's lab at the University of North Carolina Chapel Hill focuses on understanding how primary cilia, tiny antenna-like structures on neurons, influence brain function and development. They study how disruptions in primary cilia signaling can lead to neurodevelopmental disorders such as autism and epilepsy. The lab employs advanced techniques to unravel the signaling pathways and the potential therapeutic roles of primary cilia in repairing neural circuit malfunctions.
primary cilianeural circuitsneurodevelopmental disordersautismepilepsyneuron signalingciliopathyoptogeneticsbrain organoidscircuit plasticity
Research Aims
5AIM 01Investigate the signaling mechanisms utilized by primary cilia in neurons.
AIM 02Examine how primary cilia signaling influences neural circuit dynamics.
AIM 03Model human ciliopathies using brain organoids.
AIM 04Explore therapeutic approaches to mend neural circuit dysfunctions via primary cilia.
AIM 05Define cellular principles of neural circuit formation and function.
Skills the Lab Values
optogeneticschemogeneticslive imagingcellular imagingneuron culturetranscriptional profilinghuman organoid modelingdata visualizationanimal behavior analysisneural circuit mapping
Output against the department
Publications71bottom 15% of dept.244th of 286
this lab
most publishedleast published
Citations7.8ktop 42% of dept.121st of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.