WMCWeill Medical College of Cornell University · Biology
Cesarman Virology Lab
Ethel Cesarman · New York, New York
Research Focus
Dr. Ethel Cesarman's lab focuses on understanding how the Epstein-Barr virus (EBV) interacts with B cells, particularly in the context of cancers associated with HIV infection. By exploring how the virus affects B cell biology and the mechanisms that control viral protein expression, the lab aims to find new therapeutic approaches for lymphomas. This research is crucial, as people living with HIV are at significantly higher risk for developing certain types of B cell lymphomas linked to EBV.
Epstein-Barr virusB cell lymphomasHIVlatencyepigeneticsCRISPRhistone modificationtumor biologycytokinesproteomics
Research Aims
3AIM 01Identify how key germinal center cytokines affect the EBV epigenome and dictate latency program selection.
AIM 02Investigate dynamic roles of histone H1 in regulating the EBV latency program.
AIM 03Define the relationship between B-cell differentiation state and EBV latency patterns in HIV-positive DLBCL.
Skills the Lab Values
CRISPRepigenetic profilingcell cultureproteomic analysisWestern blotChIP-seqRNA sequencingflow cytometryDNA methylation analysismouse models
Output against the department
Publications386top 12% of dept.126th of 1,033
this lab
most publishedleast published
Citations31ktop 11% of dept.114th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.