New York University · Microbiology & ImmunologyViral Dynamics Lab
Angus C Wilson · New York, New York
Research Focus
Dr. Angus C. Wilson's lab studies how viruses, particularly the herpes simplex virus (HSV-1), manipulate host cell functions to enhance their replication. They explore the ways HSV-1 disrupts the host's genetic processes, particularly focusing on RNA processing and the cellular responses to stress that can trigger virus reactivation. Through their research, they hope to uncover new strategies to develop antiviral therapies against viral infections and understand their impact on the nervous system.
herpes simplex virusviral replicationhost transcriptomegene expressionneuronal stress responseRNA processingepigeneticsviral latencytherapeutic targetsnervous system
Research Aims
5AIM 01Investigate how HSV-1 alters host gene expression during infection.
AIM 02Determine the role of the viral protein ICP27 in host RNA modification disruption.
AIM 03Explore the neuronal stress response mechanisms that trigger HSV-1 reactivation.
AIM 04Characterize the effects of m6A modifications on viral and host RNA.
AIM 05Assess potential antiviral targets in the context of herpesvirus infections.
Skills the Lab Values
cell culturemolecular cloningRNA sequencingPCRWestern blotimmunoprecipitationmass spectrometryfluorescence microscopybioinformaticssingle cell analysis
Output against the department
Publications131top 50% of dept.240th of 486
this lab
most publishedleast published
Citations4.0kbottom 30% of dept.342nd of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.