University of California-Berkeley · NeuroscienceDecision Dynamics Lab
Joni D Wallis · Berkeley, California
Research Focus
Dr. Joni D Wallis's lab at UC Berkeley explores how specific brain areas, particularly the orbitofrontal cortex and caudate nucleus, influence decision-making processes. By investigating the dynamics between these regions during flexible and habitual behaviors, the lab aims to uncover how dysfunction in these circuits can lead to neuropsychiatric disorders like OCD and addiction. The research employs advanced techniques like closed-loop microstimulation to better understand the neuronal mechanisms behind learning and decision-making.
decision-makingorbitofrontal cortexcaudate nucleuscompulsive behaviorneuropsychiatric disordersmodel-based learningflexible behaviorneural circuitsmicrostimulation
Research Aims
5AIM 01Investigate how the orbitofrontal cortex inhibits automatic responses during decision-making.
AIM 02Examine the interaction between the hippocampus and orbitofrontal cortex in model-based learning.
AIM 03Explore the role of neural coherence in reward-based learning.
AIM 04Develop new devices to target specific brain circuits for therapeutic interventions.
AIM 05Understand the neuronal coding in circuits implicated in neuropsychiatric disorders.
Skills the Lab Values
closed-loop microstimulationneural recording techniquesdata analysis using population decodingbehavioral experimentationsynchronization analysiselectrophysiologypsychophysicsanimal modelscomputational modeling
Output against the department
Publications97bottom 32% of dept.452nd of 671
this lab
most publishedleast published
Citations14ktop 28% of dept.187th of 671
this lab
most citedleast cited
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