University of Florida · Microbiology & ImmunologySjogren's Disease Research Lab
Cuong Q Nguyen · Gainesville, Florida
Research Focus
Dr. Cuong Q Nguyen's lab at the University of Florida focuses on understanding Sjogren's Disease, an autoimmune disorder affecting the salivary and lacrimal glands. The lab uses advanced proteomics to uncover unique proteins that could trigger this disease. By identifying these proteins and their interactions with immune cells, the lab aims to discover new therapies to prevent or treat Sjogren's Disease, especially in those who are genetically predisposed.
Sjogren's DiseaseautoimmunityproteomicsneoepitopesHLA moleculestherapeutic targetspost-translational modificationmolecular modelingpeptide analysis
Research Aims
3AIM 01Investigate the unique proteins found in salivary glands of Sjogren's Disease patients using proteomics.
AIM 02Map the interactions between these proteins and immune system components like HLA molecules.
AIM 03Test potential therapies that disrupt harmful protein interactions to evaluate their effectiveness.
Skills the Lab Values
high-resolution proteomicsmass spectrometrymolecular modelingpeptide mappingcell culturemouse modelsimmunofluorescencedata analysisbioinformatics
Output against the department
Publications98bottom 34% of dept.321st of 486
this lab
most publishedleast published
Citations2.5kbottom 15% of dept.411th of 486
this lab
most citedleast cited
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